Tribulation

tribulation [ trib-yuh'-LEY-shuh'n ]
[ noun ]

MEANING :
1. (n.) serious trouble or suffering
2. (n.) distress or hardship

USAGE EXAMPLE 1 :
The tribulations faced by the families of the freedom fighters are often not known.

USAGE EXAMPLE 2 :
No one's immune to the trials and tribulations of life.